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Atorvastatin reverses age-related reduction in rat hepatic PPARα and HNF-4
1. Old rats are resistant to fibrate-induced hypolipidemia owing to a reduction in hepatic peroxisome proliferator-activated receptor α (PPARα). We tested whether the age-related decrease in PPARα is prevented by atorvastatin (ATV), a hypolipidemic statin. 2. We determined the activity and expressio...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1576214/ https://ncbi.nlm.nih.gov/pubmed/15912134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706260 |
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