Transgenic Expression of CXCR3 on T Cells Enhances Susceptibility to Cutaneous Leishmania major Infection by Inhibiting Monocyte Maturation and Promoting a Th2 Response

Cutaneous leishmaniasis, caused mainly by Leishmania major, an obligate intracellular parasite, is a disfiguring disease characterized by large skin lesions and is transmitted by a sand fly vector. We previously showed that the chemokine receptor CXCR3 plays a critical role in mediating resistance t...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Infect Immun
Main Authors: Oghumu, Steve, Stock, James C., Varikuti, Sanjay, Dong, Ran, Terrazas, Cesar, Edwards, Jessica A., Rappleye, Chad A., Holovatyk, Ariel, Sharpe, Arlene, Satoskar, Abhay R.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2014
נושאים:
Fungal and Parasitic Infections
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288897/
https://ncbi.nlm.nih.gov/pubmed/25312956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02540-14
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים