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MicroRNA155 Plays a Critical Role in the Pathogenesis of Cutaneous Leishmania major Infection by Promoting a Th2 Response and Attenuating Dendritic Cell Activity
Interferon (IFN)-γ is indispensable in the resolution of cutaneous leishmaniasis (CL), while the Th2 cytokines IL-4, IL-10, and IL-13 mediate susceptibility. A recent study found that miR155, which promotes CD4(+) Th1 response and IFN-γ production, is dispensable in the control of Leishmania donovan...
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| 發表在: | Am J Pathol |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Investigative Pathology
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8132173/ https://ncbi.nlm.nih.gov/pubmed/33539779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2021.01.012 |
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