CXCR3 escapes X chromosome inactivation in T cells during infection: potential implications for sex differences in immune responses

CXCR3, an X-linked gene, is subject to X-chromosome inactivation (XCI), but it is unclear whether CXCR3 escapes XCI in immune cells. We determined whether CXCR3 escapes XCI in vivo, evaluated the contribution of allelic CXCR3 expression to the phenotypic properties of T cells during experimental inf...

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Bibliografiset tiedot
Julkaisussa:J Immunol
Päätekijät: Oghumu, Steve, Varikuti, Sanjay, Stock, James C., Volpedo, Greta, Saljoughian, Noushin, Terrazas, Cesar A., Satoskar, Abhay R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684832/
https://ncbi.nlm.nih.gov/pubmed/31253729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800931
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