CXCR3 escapes X chromosome inactivation in T cells during infection: potential implications for sex differences in immune responses

CXCR3, an X-linked gene, is subject to X-chromosome inactivation (XCI), but it is unclear whether CXCR3 escapes XCI in immune cells. We determined whether CXCR3 escapes XCI in vivo, evaluated the contribution of allelic CXCR3 expression to the phenotypic properties of T cells during experimental inf...

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Bibliographic Details
Published in:J Immunol
Main Authors: Oghumu, Steve, Varikuti, Sanjay, Stock, James C., Volpedo, Greta, Saljoughian, Noushin, Terrazas, Cesar A., Satoskar, Abhay R.
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684832/
https://ncbi.nlm.nih.gov/pubmed/31253729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800931
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