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Colitis-associated cancer is dependent on the interplay between the hemostatic and inflammatory systems and supported by integrin α(M)β(2) engagement of fibrinogen
A link between colitis and colon cancer is well established, but the mechanisms regulating inflammation in this context are not fully defined. Given substantial evidence that hemostatic system components are powerful modulators of both inflammation and tumor progression, we employed gene-targeted mi...
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| Veröffentlicht in: | Cancer Res |
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| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4288842/ https://ncbi.nlm.nih.gov/pubmed/20233870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3465 |
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