Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling

BACKGROUND: Accumulation and infiltration of microglia/brain macrophages around and into glioma tissue promote tumor invasion and expansion. One tumor-promoting mechanism of microglia/brain macrophages is upregulation of membrane type 1 matrix metalloprotease (MT1-MMP), which promotes the degradatio...

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Vydáno v:Neuro Oncol
Hlavní autoři: Hu, Feng, a Dzaye, Omar Dildar, Hahn, Alexander, Yu, Yong, Scavetta, Rick Joey, Dittmar, Gunnar, Kaczmarek, Adrian Kamil, Dunning, Kylie R., Ricciardelli, Carmela, Rinnenthal, Jan L., Heppner, Frank L., Lehnardt, Seija, Synowitz, Michael, Wolf, Susanne A., Kettenmann, Helmut
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288527/
https://ncbi.nlm.nih.gov/pubmed/25452390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou324
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