Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling

BACKGROUND: Accumulation and infiltration of microglia/brain macrophages around and into glioma tissue promote tumor invasion and expansion. One tumor-promoting mechanism of microglia/brain macrophages is upregulation of membrane type 1 matrix metalloprotease (MT1-MMP), which promotes the degradatio...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuro Oncol
Prif Awduron: Hu, Feng, a Dzaye, Omar Dildar, Hahn, Alexander, Yu, Yong, Scavetta, Rick Joey, Dittmar, Gunnar, Kaczmarek, Adrian Kamil, Dunning, Kylie R., Ricciardelli, Carmela, Rinnenthal, Jan L., Heppner, Frank L., Lehnardt, Seija, Synowitz, Michael, Wolf, Susanne A., Kettenmann, Helmut
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2015
Pynciau:
Basic and Translational Investigations
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288527/
https://ncbi.nlm.nih.gov/pubmed/25452390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou324
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