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Hypothesis: cell signalling influences age-related risk of colorectal cancer
We propose that ageing is linked to colonic carcinogenesis through crosstalk between Wnt activity and signalling pathways related to ageing and senescence: progerin, klotho and mTOR. Mutations in the Wnt signalling pathway are responsible for the majority of colorectal cancers (CRCs); however, hyper...
Uloženo v:
| Vydáno v: | J Cell Mol Med |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Blackwell Publishing Ltd
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4288351/ https://ncbi.nlm.nih.gov/pubmed/25388238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12366 |
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