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Repurposing endogenous type I CRISPR-Cas systems for programmable gene repression
CRISPR-Cas systems have shown tremendous promise as heterologous tools for genome editing and transcriptional regulation. Because these RNA-directed immune systems are found in most prokaryotes, an opportunity exists to harness the endogenous systems as convenient tools in these organisms. Here, we...
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| Vydáno v: | Nucleic Acids Res |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4288209/ https://ncbi.nlm.nih.gov/pubmed/25326321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku971 |
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