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Flexibility and structural conservation in a c-KIT G-quadruplex

A quadruplex sequence from the promoter region of the c-KIT gene forms a stable quadruplex, as characterized by crystallographic and NMR methods. Two new crystal structures are reported here, together with molecular dynamics simulation studies on these quadruplex crystal structures and an NMR struct...

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書目詳細資料
發表在:Nucleic Acids Res
Main Authors: Wei, Dengguo, Husby, Jarmila, Neidle, Stephen
格式: Artigo
語言:Inglês
出版: Oxford University Press 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288176/
https://ncbi.nlm.nih.gov/pubmed/25452341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1282
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