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Flexibility and structural conservation in a c-KIT G-quadruplex

A quadruplex sequence from the promoter region of the c-KIT gene forms a stable quadruplex, as characterized by crystallographic and NMR methods. Two new crystal structures are reported here, together with molecular dynamics simulation studies on these quadruplex crystal structures and an NMR struct...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Wei, Dengguo, Husby, Jarmila, Neidle, Stephen
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288176/
https://ncbi.nlm.nih.gov/pubmed/25452341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1282
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