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Extended molecular dynamics of a c-kit promoter quadruplex

The 22-mer c-kit promoter sequence folds into a parallel-stranded quadruplex with a unique structure, which has been elucidated by crystallographic and NMR methods and shows a high degree of structural conservation. We have carried out a series of extended (up to 10 μs long, ∼50 μs in total) molecul...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Islam, Barira, Stadlbauer, Petr, Krepl, Miroslav, Koca, Jaroslav, Neidle, Stephen, Haider, Shozeb, Sponer, Jiri
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4605300/
https://ncbi.nlm.nih.gov/pubmed/26245347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv785
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