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Flexibility and structural conservation in a c-KIT G-quadruplex

A quadruplex sequence from the promoter region of the c-KIT gene forms a stable quadruplex, as characterized by crystallographic and NMR methods. Two new crystal structures are reported here, together with molecular dynamics simulation studies on these quadruplex crystal structures and an NMR struct...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Wei, Dengguo, Husby, Jarmila, Neidle, Stephen
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288176/
https://ncbi.nlm.nih.gov/pubmed/25452341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1282
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