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Toward Prospective Prediction of Pharmacokinetics in OATP1B1 Genetic Variant Populations
Physiologically based pharmacokinetic (PBPK) models are increasingly being used to provide human pharmacokinetic (PK) predictions for organic anion-transporting polypeptide (OATP) substrates based on in vitro assay data. As a natural extension in the application of these models, in this study, we in...
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| 發表在: | CPT Pharmacometrics Syst Pharmacol |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4288003/ https://ncbi.nlm.nih.gov/pubmed/25494035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/psp.2014.50 |
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