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Aptamers selected for higher-affinity binding are not more specific for the target ligand
Previous study of eleven different in vitro-selected RNA aptamers that bind guanosine triphosphate (GTP) with K(d)s ranging from 8µM to 9nM showed that more information is required to specify the structures of the higher-affinity aptamers. We are interested in understanding how the more complex apta...
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| 出版年: | J Am Chem Soc |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4287982/ https://ncbi.nlm.nih.gov/pubmed/16771507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja060952q |
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