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An Anti-CD154 Domain Antibody Prolongs Graft Survival and Induces FoxP3(+) iTreg in the Absence and Presence of CTLA-4 Ig

The use of monoclonal antibodies targeting the CD154 molecule remains one of the most effective means of promoting graft tolerance in animal models, but thromboembolic complications during early clinical trials have precluded their use in humans. Furthermore, the role of Fc-mediated deletion of CD15...

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Detalhes bibliográficos
Publicado no:Am J Transplant
Main Authors: Pinelli, DF, Wagener, ME, Liu, D, Yamniuk, A, Tamura, J, Grant, S, Larsen, CP, Suri, A, Nadler, SG, Ford, ML
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287239/
https://ncbi.nlm.nih.gov/pubmed/24007441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.12417
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