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Rapamycin ameliorates the CTLA4-Ig-mediated defect in CD8(+) T cell immunity during gammaherpesvirus infection
Latent viral infections are a major concern among immunosuppressed transplant patients. During clinical trials with belatacept, a CTLA4-Ig fusion protein, patients showed an increased risk of Epstein-Barr Virus-associated post-transplant lymphoproliferative disorder, thought to be due to a deficient...
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| Publicat a: | Am J Transplant |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389899/ https://ncbi.nlm.nih.gov/pubmed/25989700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13326 |
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