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Short Communication: SAHA (Vorinostat) Induces CDK9 Thr-186 (T-Loop) Phosphorylation in Resting CD4(+) T Cells: Implications for Reactivation of Latent HIV
The histone deacetylase inhibitor (HDACi) suberoylanilide hydroxyamic acid (SAHA), also known as vorinostat, has recently been reported to activate latent HIV-1 in patients undergoing antiretroviral therapy. It is possible that SAHA reactivation of latent viruses may involve effects on cellular tran...
Gespeichert in:
| Veröffentlicht in: | AIDS Res Hum Retroviruses |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Mary Ann Liebert, Inc.
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4287136/ https://ncbi.nlm.nih.gov/pubmed/24528253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2013.0288 |
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