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Cdk9 T-loop Phosphorylation is Regulated by the Calcium Signaling Pathway

Eukaryotic RNA polymerase II transcriptional elongation is a tightly regulated process and is dependent upon positive transcription elongation factor-b (P-TEFb). The core P-TEFb complex is composed of Cdk9 and Cyclin T and is essential for the expression of most protein coding genes. Cdk9 kinase fun...

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Autors principals: Ramakrishnan, Rajesh, Rice, Andrew P.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146566/
https://ncbi.nlm.nih.gov/pubmed/21448926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22760
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