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Characterization of Cdk9 T-loop phosphorylation in resting and activated CD4(+) T lymphocytes
The cellular kinase complex P-TEFb is composed of Cdk9 and cyclin T, and it is required for expression of most protein-coding genes by RNAP II. Cdk9 has been shown recently to be activated in cis by autophosphorylation of Thr186 in its T-loop. Using a phosphospecific Cdk9 antibody, we examined the l...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Society for Leukocyte Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2780919/ https://ncbi.nlm.nih.gov/pubmed/19741158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0509309 |
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