Autophagy mediates HIF2α degradation and suppresses renal tumorigenesis

Autophagy is a conserved process involved in lysosomal degradation of protein aggregates and damaged organelles. The role of autophagy in cancer is a topic of intense debate, and the underlying mechanism is still not clear. The hypoxia inducible factor 2α (HIF2α), an oncogenic transcription factor i...

詳細記述

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書誌詳細
出版年:Oncogene
主要な著者: Liu, Xian-De, Yao, Jun, Tripathi, Durga Nand, Ding, Zhiyong, Xu, Yi, Sun, Mianen, Zhang, Jiangwei, Bai, Shanshan, German, Peter, Hoang, Anh, Zhou, Lijun, Jonasch, Darius, Zhang, Xuesong, Conti, Claudio J., Efstathiou, Eleni, Tannir, Nizar M, Eissa, N. Tony, Mills, Gordon B., Walker, Cheryl Lyn, Jonasch, Eric
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286517/
https://ncbi.nlm.nih.gov/pubmed/24998849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.199
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