Autophagy mediates HIF2α degradation and suppresses renal tumorigenesis

Autophagy is a conserved process involved in lysosomal degradation of protein aggregates and damaged organelles. The role of autophagy in cancer is a topic of intense debate, and the underlying mechanism is still not clear. The hypoxia inducible factor 2α (HIF2α), an oncogenic transcription factor i...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Liu, Xian-De, Yao, Jun, Tripathi, Durga Nand, Ding, Zhiyong, Xu, Yi, Sun, Mianen, Zhang, Jiangwei, Bai, Shanshan, German, Peter, Hoang, Anh, Zhou, Lijun, Jonasch, Darius, Zhang, Xuesong, Conti, Claudio J., Efstathiou, Eleni, Tannir, Nizar M, Eissa, N. Tony, Mills, Gordon B., Walker, Cheryl Lyn, Jonasch, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286517/
https://ncbi.nlm.nih.gov/pubmed/24998849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.199
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