LASP1 is a HIF-1α target gene critical for metastasis of pancreatic cancer

LASP1 is an actin-binding protein associated with actin assembly dynamics in cancer cells. Here we report that LASP1 is overexpressed in pancreatic ductal adenocarcinoma (PDAC) where it promotes invasion and metastasis. We found that LASP1 overexpression in PDAC cells was mediated by HIF-1α through...

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Dades bibliogràfiques
Publicat a:Cancer Res
Autors principals: Zhao, Tiansuo, Ren, He, Li, Jing, Chen, Jing, Zhang, Huan, Xin, Wen, Sun, Yan, Sun, Lei, Yang, Yongwei, Sun, Junwei, Wang, Xiuchao, Gao, Song, Huang, Chongbiao, Zhang, Huafeng, Yang, Shengyu, Hao, Jihui
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286473/
https://ncbi.nlm.nih.gov/pubmed/25385028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2040
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