LASP1 is a HIF-1α target gene critical for metastasis of pancreatic cancer

LASP1 is an actin-binding protein associated with actin assembly dynamics in cancer cells. Here we report that LASP1 is overexpressed in pancreatic ductal adenocarcinoma (PDAC) where it promotes invasion and metastasis. We found that LASP1 overexpression in PDAC cells was mediated by HIF-1α through...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Res
Egile Nagusiak: Zhao, Tiansuo, Ren, He, Li, Jing, Chen, Jing, Zhang, Huan, Xin, Wen, Sun, Yan, Sun, Lei, Yang, Yongwei, Sun, Junwei, Wang, Xiuchao, Gao, Song, Huang, Chongbiao, Zhang, Huafeng, Yang, Shengyu, Hao, Jihui
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286473/
https://ncbi.nlm.nih.gov/pubmed/25385028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2040
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