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Functional Interaction Between Amyloid-β Precursor Protein and Peripherin Neurofilaments: A Shared Pathway Leading to Alzheimer’s Disease and Amyotrophic Lateral Sclerosis?

BACKGROUND AND OBJECTIVE: The pathology of amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder affecting motor neurons, comprises aberrant accumulations of neurofilaments; mutations in the peripherin subunit of neurofilaments have been identified in some forms of ALS. Recently, the Amy...

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Detalhes bibliográficos
Publicado no:Neurodegener Dis
Main Authors: Muresan, Virgil, Villegas, Christine, Muresan, Zoia Ladescu
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286376/
https://ncbi.nlm.nih.gov/pubmed/24009040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000354238
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