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Shared Molecular Mechanisms in Alzheimer’s Disease and Amyotrophic Lateral Sclerosis: Neurofilament-dependent Transport of sAPP, FUS, TDP-43, and SOD1, with Endoplasmic Reticulum-like Tubules
BACKGROUND: Amyotrophic lateral sclerosis (ALS), a debilitating neurodegenerative disorder of the motor neurons, leads to the disorganization of the neurofilament (NF) cytoskeleton, and – ultimately - the deterioration of the neuromuscular junction (NMJ). Some familial cases of ALS are caused by mut...
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| Vydáno v: | Neurodegener Dis |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4681536/ https://ncbi.nlm.nih.gov/pubmed/26605911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000439256 |
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