Validation and implementation of a liquid chromatography/tandem mass spectrometry assay to quantitate ON 01910.Na, a mitotic progression modulator, in human plasma

A reverse-phase high performance liquid chromatographic method with tandem mass spectrometry (LC-MS/MS) was developed and validated for the quantitation of ON 01910.Na, a novel synthetic benzyl styryl sulfone, in human plasma. The assay involved a simple sample preparation with acetonitrile protein...

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Publicado en:J Chromatogr B Analyt Technol Biomed Life Sci
Autores principales: Li, Jing, Zhao, Ming, Jimeno, Antonio, He, Ping, Ramana Reddy, M. V., Hidalgo, Manuel, Donehower, Ross C., Rudek, Michelle A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286291/
https://ncbi.nlm.nih.gov/pubmed/17588831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2007.05.047
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