Application of a liquid chromatography – tandem mass spectrometry (LC/MS/MS) method to the pharmacokinetics of ON01910 in brain tumor-bearing mice

ON01910 is a small molecular weight benzyl styryl sulfone currently under investigation as a novel anticancer agent. The purpose of the investigation was to develop a sensitive and reproducible liquid chromatography-tandem mass spectrometry (LC/MS/MS) method to quantitate levels of ON01910 in small...

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Hauptverfasser: Nuthalapati, Silpa, Guo, Ping, Zhou, Qingyu, Ramana Reddy, M. V., Reddy, E. Premkumar, Gallo, James M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176944/
https://ncbi.nlm.nih.gov/pubmed/21880454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2011.08.003
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