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A Two – Compartment Population Pharmacokinetic-Pharmacodynamic Model of Digoxin in Adults, with Implications for Dosage
A population pharmacokinetic/pharmacodynamic (PK/PD) model of digoxin in adult subjects was originally developed by Reuning et al in 1973. They clearly described the two - compartment behavior of digoxin, the lack of correlation of effect with serum concentrations, and the close correlation of the o...
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| Udgivet i: | Ther Drug Monit |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4286255/ https://ncbi.nlm.nih.gov/pubmed/24492383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FTD.0000000000000023 |
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