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A Two – Compartment Population Pharmacokinetic-Pharmacodynamic Model of Digoxin in Adults, with Implications for Dosage

A population pharmacokinetic/pharmacodynamic (PK/PD) model of digoxin in adult subjects was originally developed by Reuning et al in 1973. They clearly described the two - compartment behavior of digoxin, the lack of correlation of effect with serum concentrations, and the close correlation of the o...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Ther Drug Monit
Päätekijät: Jelliffe, Roger, Milman, Mark, Schumitzky, Alan, Bayard, David, Van Guilder, Michael
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286255/
https://ncbi.nlm.nih.gov/pubmed/24492383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FTD.0000000000000023
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