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Improved 2-Compartment Time-Shared Programs for Adaptive Control of Digitoxin and Digoxin Therapy

Computer programs for adaptive control of digitoxin and digoxin therapy have been developed using a 2-compartment pharmacokinetic model. The amount of drug in the peripheral compartment correlates with inotropic effect of the drug. Therapeutic goals are stated as a desired peak total body glycoside...

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Détails bibliographiques
Auteurs principaux: Jelliffe, Roger W., Schumitzky, Alan, D'Argenio, David Z., Katz, Darryl, Rodman, John
Format: Artigo
Langue:Inglês
Publié: 1983
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2578431/
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