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Efficacy of Nelfinavir as Monotherapy in Refractory Adenoid Cystic Carcinoma: Results of a Phase II Clinical Trial
BACKGROUND: Adenoid cystic carcinoma (ACCs) are malignant salivary gland tumors noteworthy for high rates of late failure with limited salvage therapy options. We have previously shown increased Akt signaling is common in ACC and the HIV protease inhibitor nelfinavir (NFV) inhibits in vitro tumor gr...
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| Publicado no: | Head Neck |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4285572/ https://ncbi.nlm.nih.gov/pubmed/24596143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hed.23664 |
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