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Phase I trial of isatuximab monotherapy in the treatment of refractory multiple myeloma

This phase I dose-escalation/expansion study evaluated isatuximab (anti-CD38 monoclonal antibody) monotherapy in patients with relapsed/refractory multiple myeloma (RRMM). Patients progressing on or after standard therapy received intravenous isatuximab (weekly [QW] or every 2 weeks [Q2W]). The prim...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Blood Cancer J
Prif Awduron: Martin, Thomas, Strickland, Stephen, Glenn, Martha, Charpentier, Eric, Guillemin, Hélène, Hsu, Karl, Mikhael, Joseph
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440961/
https://ncbi.nlm.nih.gov/pubmed/30926770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-019-0198-4
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