Efficacy of Nelfinavir as Monotherapy in Refractory Adenoid Cystic Carcinoma: Results of a Phase II Clinical Trial

BACKGROUND: Adenoid cystic carcinoma (ACCs) are malignant salivary gland tumors noteworthy for high rates of late failure with limited salvage therapy options. We have previously shown increased Akt signaling is common in ACC and the HIV protease inhibitor nelfinavir (NFV) inhibits in vitro tumor gr...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Head Neck
Autori principali: Hoover, Andrew C, Milhem, Mohammed M, Anderson, Carryn M, Sun, Wenqing, Smith, Brian J, Hoffman, Henry T, Buatti, John M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285572/
https://ncbi.nlm.nih.gov/pubmed/24596143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hed.23664
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi