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Protein conjugation with genetically encoded unnatural amino acids

The site-specific incorporation of unnatural amino acids with orthogonal chemical reactivity into proteins enables the synthesis of structurally-defined protein conjugates. Amino acids containing ketone, azide, alkyne, alkene, and tetrazine side chains can be genetically encoded in response to nonse...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Curr Opin Chem Biol
Main Authors: Kim, Chan Hyuk, Axup, Jun Y., Schultz, Peter G.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284959/
https://ncbi.nlm.nih.gov/pubmed/23664497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2013.04.017
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