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Chiral sulfinamidourea/Strong Brønsted Acid co-catalyzed enantioselective Povarov reaction to access tetrahydroquinolines
This protocol describes a method for the laboratory synthesis of chiral tetrahydroisoquinolines, bicyclic organic framework present in a wide assortment of natural and synthetic biologically important compounds. The methodology involves the use of a two-catalyst system: an achiral strong Brønsted ac...
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| Publicado en: | Nat Protoc |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4284825/ https://ncbi.nlm.nih.gov/pubmed/25010906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2014.125 |
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