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STAT3 promotes survival of mutant photoreceptors in inherited photoreceptor degeneration models

Inherited photoreceptor degenerations (IPDs), a group of incurable progressive blinding diseases, are caused by mutations in more than 200 genes, but little is known about the molecular pathogenesis of photoreceptor (PR) death. Increased retinal expression of STAT3 has been observed in response to m...

詳細記述

保存先:
書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Jiang, Ke, Wright, Katherine L., Zhu, Ping, Szego, Michael J., Bramall, Alexa N., Hauswirth, William W., Li, Qiuhong, Egan, Sean E., McInnes, Roderick R.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284576/
https://ncbi.nlm.nih.gov/pubmed/25512545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411248112
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