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PIP(2)-dependent coupling is prominent in Kv7.1 due to weakened interactions between S4-S5 and S6

Among critical aspects of voltage-gated potassium (Kv) channels' functioning is the effective communication between their two composing domains, the voltage sensor (VSD) and the pore. This communication, called coupling, might be transmitted directly through interactions between these domains a...

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Publicat a:Sci Rep
Autors principals: Kasimova, Marina A., Zaydman, Mark A., Cui, Jianmin, Tarek, Mounir
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284513/
https://ncbi.nlm.nih.gov/pubmed/25559286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07474
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