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Immortalization of Human Fetal Hepatocyte by Ectopic Expression of Human Telomerase Reverse Transcriptase, Human Papilloma Virus (E7) and Simian Virus 40 Large T (SV40 T) Antigen Towards Bioartificial Liver Support

BACKGROUND: Generation of genetically stable and non-tumoric immortalization cell line from primary cells would be enormously useful for research and therapeutic purposes, but progress towards this goal has so far been limited. It is now universal acceptance that immortalization of human fetal hepat...

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Detalhes bibliográficos
Publicado no:J Clin Exp Hepatol
Main Authors: Giri, Shibashish, Bader, Augustinus
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284290/
https://ncbi.nlm.nih.gov/pubmed/25755560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jceh.2014.08.001
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