Immortalization of human fibroblasts transformed by origin-defective simian virus 40.

Simian virus 40 (SV40)-mediated transformation of human diploid fibroblasts has provided an effective experimental system for studies of both "senescence" in cell culture and carcinogenesis. Previous interpretations may have been complicated, however, by the semipermissive virus-cell inter...

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Bibliographic Details
Main Authors: Neufeld, D S, Ripley, S, Henderson, A, Ozer, H L
Format: Artigo
Language:Inglês
Published: 1987
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC367896/
https://ncbi.nlm.nih.gov/pubmed/2823105
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