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Immortalization of Human Fetal Hepatocyte by Ectopic Expression of Human Telomerase Reverse Transcriptase, Human Papilloma Virus (E7) and Simian Virus 40 Large T (SV40 T) Antigen Towards Bioartificial Liver Support

BACKGROUND: Generation of genetically stable and non-tumoric immortalization cell line from primary cells would be enormously useful for research and therapeutic purposes, but progress towards this goal has so far been limited. It is now universal acceptance that immortalization of human fetal hepat...

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Veröffentlicht in:J Clin Exp Hepatol
Hauptverfasser: Giri, Shibashish, Bader, Augustinus
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284290/
https://ncbi.nlm.nih.gov/pubmed/25755560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jceh.2014.08.001
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