Aberrantly activated pSTAT3-ser727 in human endometrial cancer is suppressed by HO-3867, a novel STAT3 inhibitor

OBJECTIVE: Constitutive activation of STAT3 is a hallmark of various human cancers, although an increased pSTAT3 expression in high grade human endometrial cancer has not been reported. In the present study, we examine the expression of STAT family of proteins in endometrial cancer cell lines and th...

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Pubblicato in:Gynecol Oncol
Autori principali: Tierney, Brent J., McCann, Georgia A., Naidu, Shan, Rath, Kellie S., Saini, Uksha, Wanner, Ross, Kuppusamy, Periannan, Suarez, Adrian, Goodfellow, Paul J., Cohn, David E., Selvendiran, Karuppaiyah
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283766/
https://ncbi.nlm.nih.gov/pubmed/25038288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2014.07.087
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