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Data-driven treatment selection for seamless phase II/III trials incorporating early-outcome data
Seamless phase II/III clinical trials are conducted in two stages with treatment selection at the first stage. In the first stage, patients are randomized to a control or one of k > 1 experimental treatments. At the end of this stage, interim data are analysed, and a decision is made concerning w...
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| Pubblicato in: | Pharm Stat |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BlackWell Publishing Ltd
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4283755/ https://ncbi.nlm.nih.gov/pubmed/24789367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pst.1619 |
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