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Flexible selection of a single treatment incorporating short‐term endpoint information in a phase II/III clinical trial

Seamless phase II/III clinical trials in which an experimental treatment is selected at an interim analysis have been the focus of much recent research interest. Many of the methods proposed are based on the group sequential approach. This paper considers designs of this type in which the treatment...

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Bibliografski detalji
Izdano u:Stat Med
Glavni autori: Stallard, Nigel, Kunz, Cornelia Ursula, Todd, Susan, Parsons, Nicholas, Friede, Tim
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745001/
https://ncbi.nlm.nih.gov/pubmed/26112909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6567
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