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Interim analysis incorporating short‐ and long‐term binary endpoints

Designs incorporating more than one endpoint have become popular in drug development. One of such designs allows for incorporation of short‐term information in an interim analysis if the long‐term primary endpoint has not been yet observed for some of the patients. At first we consider a two‐stage d...

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Dades bibliogràfiques
Publicat a:Biom J
Autors principals: Niewczas, Julia, Kunz, Cornelia U., König, Franz
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590444/
https://ncbi.nlm.nih.gov/pubmed/30694566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bimj.201700281
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