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XPO1/CRM1-Selective Inhibitors of Nuclear Export (SINE) reduce tumor spreading and improve overall survival in preclinical models of prostate cancer (PCa)
BACKGROUND: Exportin 1 (XPO1), also called chromosome region maintenance 1 (CRM1), is the sole exportin mediating transport of many multiple tumor suppressor proteins out of the nucleus. AIM AND METHODS: To verify the hypothesis that XPO1 inhibition affects prostate cancer (PCa) metastatic potential...
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| Pubblicato in: | J Hematol Oncol |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4283114/ https://ncbi.nlm.nih.gov/pubmed/25284315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-7-46 |
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