The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope

The Killer cell Immunoglobulin-like Receptor 3DL1 (KIR3DL1) inhibits activation of Natural Killer (NK) cells upon interaction with Human Leukocyte Antigen (HLA) class I molecules such as HLA-B*57:01 which contain the Bw4 epitope spanning residues 77-83 (e.g. NLRIALR) and not with HLA allomorphs that...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Immunol
Hlavní autoři: Saunders, Philippa M., Vivian, Julian P., Baschuk, Nikola, Beddoe, Travis, Widjaja, Jacqueline, O'Connor, Geraldine M., Hitchen, Corinne, Pymm, Phillip, Andrews, Daniel M., Gras, Stephanie, McVicar, Daniel W., Rossjohn, Jamie, Brooks, Andrew G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282956/
https://ncbi.nlm.nih.gov/pubmed/25480565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402542
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky