Common HIV-1 Peptide Variants Mediate Differential Binding of KIR3DL1 to HLA-Bw4 Molecules

Epidemiological studies have shown the protective effect of KIR3DL1/HLA-Bw4 genotypes in human immunodeficiency virus type 1 (HIV-1) infection; however, the functional correlates for the protective effect remain unknown. We investigated whether human leukocyte antigen (HLA)-Bw4-presented HIV-1 pepti...

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Main Authors: Fadda, Lena, O'Connor, Geraldine M., Kumar, Swati, Piechocka-Trocha, Alicja, Gardiner, Clair M., Carrington, Mary, McVicar, Daniel W., Altfeld, Marcus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126328/
https://ncbi.nlm.nih.gov/pubmed/21471246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00412-11
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