The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope

The Killer cell Immunoglobulin-like Receptor 3DL1 (KIR3DL1) inhibits activation of Natural Killer (NK) cells upon interaction with Human Leukocyte Antigen (HLA) class I molecules such as HLA-B*57:01 which contain the Bw4 epitope spanning residues 77-83 (e.g. NLRIALR) and not with HLA allomorphs that...

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Xehetasun bibliografikoak
Argitaratua izan da:J Immunol
Egile Nagusiak: Saunders, Philippa M., Vivian, Julian P., Baschuk, Nikola, Beddoe, Travis, Widjaja, Jacqueline, O'Connor, Geraldine M., Hitchen, Corinne, Pymm, Phillip, Andrews, Daniel M., Gras, Stephanie, McVicar, Daniel W., Rossjohn, Jamie, Brooks, Andrew G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282956/
https://ncbi.nlm.nih.gov/pubmed/25480565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402542
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